Closys vs. Listerine Mouthwash: Key Differences, Specs Comparison, Review

The key difference between Closys and Listerine lies in their formulations, active ingredients, and approach to oral care. Both these products have their unique advantages and similarities. In this article, we will explore their common features and compare them side by side to help you make an informed decision. With so many similarities, how do you choose between the two? Let’s explore this by examining the key differences.

7 Key Differences

  1. Active Ingredients:
  • Closys: The active ingredient in Closys is stabilized chlorine dioxide, known for its powerful antibacterial properties. It neutralizes harmful bacteria and prevents plaque buildup effectively.
  • Listerine: Listerine contains a blend of essential oils, such as eucalyptol, menthol, thymol, and methyl salicylate. These oils work together to fight bacteria and reduce gingivitis. Suitability: For users looking for a more natural approach, Listerine’s essential oil blend might be preferable. On the other hand, Closys could be the choice for those seeking a clinically proven antibacterial agent.
  1. Alcohol Content:
  • Closys: One significant advantage of Closys is its alcohol-free formula, making it a gentler option for individuals with sensitive gums or a history of mouth dryness.
  • Listerine: Listerine contains alcohol, which might cause a burning sensation and irritation in some users, particularly those with sensitive oral tissues. Suitability: If you have sensitive gums or dislike the burning sensation caused by alcohol-based mouthwashes, Closys would be a better option.
  1. Fluoride Content:
  • Closys: Unlike Listerine, Closys does not contain fluoride. For some users, this might be a drawback as fluoride helps strengthen teeth and prevent cavities.
  • Listerine: Listerine mouthwashes often include fluoride, which provides additional protection against tooth decay and enamel erosion. Suitability: If you value the benefits of fluoride in your oral care routine, Listerine would be the suitable choice.
  1. Usage Frequency:
  • Closys: Due to its potent antibacterial action, Closys is recommended for use twice daily. Using it more frequently might lead to overuse of chlorine dioxide.
  • Listerine: Listerine can be used twice daily like Closys, but some variants are suitable for daily use or even multiple times a day. Suitability: For users seeking a mouthwash they can use several times a day, Listerine provides more options.
  1. Taste and Sensation:
  • Closys: Closys has a milder taste and does not leave a strong aftertaste, which makes it more appealing to some users.
  • Listerine: Listerine’s essential oils contribute to its strong taste and the characteristic tingling sensation that might not be enjoyable for everyone. Suitability: If you prefer a less intense taste and sensation, Closys would be a better fit.
  1. Whitening Properties:
  • Closys: While Closys primarily focuses on killing bacteria and maintaining oral health, it does not have specific whitening properties.
  • Listerine: Some Listerine variants are designed to help with teeth whitening, providing an added benefit for users looking to brighten their smile. Suitability: If teeth whitening is one of your priorities, consider opting for a Listerine whitening variant.
  1. Antiseptic vs. Plaque Control:
  • Closys: The key strength of Closys lies in its antiseptic properties, targeting bacteria and bad breath, while also promoting gum health.
  • Listerine: Listerine emphasizes plaque control, reducing plaque and gingivitis effectively, but it also addresses bad breath. Suitability: If you have specific concerns regarding gum health, Closys could be the preferred choice. However, if plaque control is your primary concern, Listerine might be more suitable.

Comparison Table

Active IngredientsStabilized chlorine dioxideEssential oils (eucalyptol, menthol, thymol, methyl salicylate)
Alcohol ContentAlcohol-freeContains alcohol
Fluoride ContentNo fluorideSome variants contain fluoride
Usage FrequencyTwice dailyVaried (daily use or multiple times a day)
Taste and SensationMilder taste, no strong aftertasteStrong taste, tingling sensation
Whitening PropertiesFocuses on oral health, no whiteningSome variants offer teeth whitening
Antiseptic vs. Plaque ControlEmphasizes antiseptic propertiesEmphasizes plaque control, also addresses bad breath

Reviews of Popular Versions

Closys Versions

  1. Closys Fresh Breath Oral Rinse
  • Key Specs: Alcohol-free, stabilized chlorine dioxide formula, designed for daily use.
  • Pros: Powerful antibacterial action, fights bad breath effectively, gentle on sensitive gums.
  • Cons: Does not include fluoride, no specific whitening properties.
  1. Closys Ultra Sensitive Mouthwash
  • Key Specs: Specially formulated for sensitive gums, alcohol-free, and non-irritating.
  • Pros: Ideal for individuals with mouth dryness or sensitivity, promotes oral health.
  • Cons: Lack of fluoride might be a drawback for some users.
  1. Closys Fluoride Mouthwash
  • Key Specs: Includes fluoride for added tooth protection, alcohol-free formula.
  • Pros: Provides cavity protection, antibacterial benefits, suitable for daily use.
  • Cons: Taste might not be as appealing to some users.

Listerine Versions

  1. Listerine Cool Mint Antiseptic Mouthwash
  • Key Specs: Contains essential oils, alcohol-based, recommended for twice-daily use.
  • Pros: Effective plaque control, fights gingivitis, leaves a fresh feeling.
  • Cons: Burning sensation due to alcohol content, not suitable for sensitive gums.
  1. Listerine Total Care Zero Alcohol Mouthwash
  • Key Specs: Alcohol-free, contains fluoride, promotes oral health.
  • Pros: Provides comprehensive oral care, fights bacteria, and cavities.
  • Cons: Some users might find the taste overpowering.

Frequently Asked Questions (FAQ)

1. Can I use Closys or Listerine if I have sensitive gums?

  • Yes, both Closys and Listerine offer options suitable for individuals with sensitive gums. Closys Ultra Sensitive Mouthwash is specifically formulated to be gentle on sensitive gums, while Listerine Total Care Zero Alcohol Mouthwash is alcohol-free, making it a milder choice for sensitive oral tissues.

2. Do Closys and Listerine contain fluoride?

  • Closys does not contain fluoride in its formula, whereas some variants of Listerine do include fluoride. If you prioritize the benefits of fluoride in preventing cavities and strengthening teeth, consider choosing a Listerine variant with fluoride.

3. Which mouthwash is better for fighting bad breath?

  • Both Closys and Listerine are effective in fighting bad breath. Closys’ stabilized chlorine dioxide neutralizes bacteria that cause bad breath, while Listerine’s essential oil blend also helps combat foul odors. The choice between the two would depend on other factors like taste preferences and alcohol content.

4. Can I use Closys or Listerine more than twice daily?

  • It is recommended to use Closys and Listerine twice daily, as excessive use might lead to overuse of certain active ingredients. However, some Listerine variants are suitable for daily use or even multiple times a day, so check the instructions on the product’s label.

5. Do these mouthwashes help with teeth whitening?

  • Closys does not have specific whitening properties, but some Listerine variants are designed to offer teeth whitening benefits. If teeth whitening is one of your priorities, consider opting for a Listerine whitening variant.


In conclusion, Closys and Listerine are both reputable mouthwash brands with unique features to address different oral care needs. Closys stands out with its powerful antibacterial action, making it suitable for users seeking an antiseptic option without alcohol. Listerine, on the other hand, emphasizes plaque control and offers diverse variants, including some with fluoride for additional tooth protection.

Choosing between Closys and Listerine depends on your personal preferences and specific oral health requirements. Consider factors such as active ingredients, alcohol content, fluoride inclusion, and taste sensation when making your decision.

Always remember to follow the usage instructions on the product label and consult your dentist if you have any specific oral health concerns or conditions.


The choice between Closys and Listerine ultimately depends on your specific needs and preferences. Both products offer effective oral care solutions, but they differ in their active ingredients, alcohol content, fluoride inclusion, and overall approach to oral health.

If you prioritize a natural and alcohol-free option with powerful antibacterial properties, Closys could be the right fit for you. On the other hand, if you seek a mouthwash that emphasizes plaque control and offers teeth whitening benefits, Listerine might be more suitable.

Ultimately, the decision comes down to your individual oral health requirements, taste preferences, and sensitivity levels.

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Last update on 2023-12-11 / Affiliate links / Images from Amazon Product Advertising API

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